منابع مشابه
Metal Complexes in Drug Research - A Review
Metal compounds provide new opportunities for building structures with defined properties. A number of diseases and their treatment dependent on the metabolism of inorganic constituents. The advances in inorganic chemistry provide better opportunities to use metal complexes as therapeutic agents. The mode of action of metal complexes on living organism is differing from non metals. These comple...
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Summarizing the status of drugs in the market and examining the trend of drug research and development is important in drug discovery. In this study, we compared the drug targets and the market sales of the new molecular entities approved by the U.S. Food and Drug Administration from January 2000 to December 2009. Two networks, namely, the target-target and drug-drug networks, have been set up ...
متن کاملMetal-Based Drug-DNA Interactions
Coordination compounds that bind to DNA have been an active area of research since the discovery of cisplatin and the platinum based drugs. In this review we offer a general overview about transition-metal compounds that binds DNA through several ways and some examples are given to understand the role played by the different factors that promotes it, such as the intercalant ligand and the natur...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2015
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.14-00227-f